Volume 23, Issue 4 p. 931-938
Full Paper

Nickel Nanoparticle Modified BDD Electrode Shows an Electrocatalytic Response to Adenine and DNA in Aqueous Alkaline Media

John C. Harfield

John C. Harfield

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford, OX1 3QZ, United Kingdom

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Kathryn E. Toghill

Kathryn E. Toghill

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford, OX1 3QZ, United Kingdom

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Christopher Batchelor-McAuley

Christopher Batchelor-McAuley

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford, OX1 3QZ, United Kingdom

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Clive Downing

Clive Downing

Begbroke Science Park, Sandy Lane, Yarnton, Oxford, OX5 1PF, United Kingdom

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Richard G. Compton

Corresponding Author

Richard G. Compton

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford, OX1 3QZ, United Kingdom

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford, OX1 3QZ, United KingdomSearch for more papers by this author
First published: 16 March 2011
Citations: 35

Abstract

The electrooxidation of adenine, guanine and DNA was investigated under alkaline conditions at unmodified (BDDE) and at a nickel nanoparticle modified boron-doped diamond electrodes (Ni-BDDE). An oxidative response was observed at the Ni-BDDE for each analyte, particularly notable of the adenine as the oxidation overpotential was reduced to below 0.5 V vs. SCE, and was otherwise unobserved at the unmodified electrode.